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💊 Medicine EU March 23, 2026

Eli Lilly insulin (various forms)

📷 EU Safety Watch placeholder
Eli Lilly insulin (various forms)
📷 EU Safety Watch placeholder
Forms
Solution for injection;Suspension for injection
Alternatives
Yes
⚠️
Shortage ongoing
is currently in short supply in EU.
📈 Timeline
73 days active so far
May 16, 2026 July 27, 2026

What is this? This is insulin made by Eli Lilly. It comes as a liquid or a mix you inject under the skin.

What's happening? Some forms of this insulin are in short supply right now.

Does this affect me? If you use Eli Lilly insulin, you may be affected.

What should I do? Talk to your pharmacist or doctor before changing your dose or brand.

🤖 This plain-language summary is automatically generated from the official agency notice using AI. It is for general information only — not medical advice. For decisions about your health, always consult a pharmacist or doctor and read the official source linked below.

📋 From the official agency notice

Updated 2 months ago
First published
23/03/2026
Medicines affected
Eli Lilly insulin (various forms)
Supply shortage status
Ongoing
Availability of alternatives
Yes
Pharmaceutical forms affected
Solution for injectionSuspension for injection

Page contents

Shortage information

Eli Lilly is discontinuing some of its insulin presentations (containing human insulin, insulin lispro and insulin glargine) across selected countries. The specific products affected and the timelines for their withdrawal differ across EU/EEA countries. All discontinuations are expected to occur before Q2 2027, after which the affected insulin presentations will no longer be available.

This is in addition to Humalog Mix25 (25% insulin lispro and 75% insulin lispro protamine, 100 units/ml suspension for injection, vial) which has already been discontinued in all EU/EEA countries where it was marketed.

Insulin medicines are used to treat patients who have diabetes and need insulin to help control their blood glucose (sugar) level.

For information on the use of the medicines please refer to the respective medicine overview pages on EMA’s website.

For more details and up-to-date information on the availability of individual insulins, consult your country’s shortage register or contact your national competent authority. 

The company Eli Lilly has decided to stop marketing some of its insulin medicines for commercial reasons. This decision is not related to a quality defect or safety issue. 

The discontinuations affect Member States differently. For more details, consult your country’s shortage register or contact your national competent authority. 

EMA’s Executive Steering Group on Shortages and Safety of Medicinal Products (MSSG) and EMA’s shortages working party (Medicines Shortages Single Point of Contact – SPOC - working party) are closely monitoring the supply situation and engaging with the marketing authorisation holder and other stakeholders to mitigate the impact of the planned discontinuations.

The SPOC Working Party Supports EMA’s MSSG and monitors and reports events that could affect the supply of medicines in the EU.

  • For information specific to your country, please consult your national shortage register or contact your national competent authority.
  • In affected Member States, healthcare professionals will receive a shortage communication letter with details on the impacted insulins and recommended actions.
  • Where applicable, healthcare professionals should transition patients currently using any of the affected insulins to suitable alternatives, in line with existing guidance and their clinical judgement.
  • Healthcare professionals should ensure that all patients are counselled on any changes in the new insulin regimen including the need to change dose and/or usage of the new insulin delivery system and additional glucose monitoring.
  • Close glucose monitoring is recommended when the patient is switched to another type or brand of insulin and in the initial weeks thereafter, especially in pregnant women and children who may need closer monitoring than the general population. The risk of hypoglycaemia may be higher in these populations.
  • Healthcare professionals may also contact relevant organisations for further information. A list of European not-for-profit organisations EMA engages with can be found on the EMA website.

  • For information specific to your country, please consult your national shortage register or contact your healthcare professional.
  • Your healthcare professional will advise you if any of the insulins you are using are affected by the discontinuation and will switch you to an alternative insulin, if needed.
  • If your healthcare professional switches your insulin they will explain any changes to you and ensure that you are given adequate training on using any new insulin delivery system.
  • If you are being switched, you may need to closely monitor your glucose levels during the transfer to another type or brand of insulin and in the initial weeks thereafter. This applies especially if you are pregnant or under 18 years of age, as you may be at higher risk of hypoglycaemia.
  • If you have any questions, speak to your doctor or pharmacist.
  • You may also contact relevant patients’ organisations for further information or support. A list of European not-for-profit organisations that EMA engages with can be found on the EMA website.
  • For additional information, consult your country’s shortage register or contact your national competent authority. 

Reason for shortage

The company Eli Lilly has decided to stop marketing some of its insulin medicines for commercial reasons. This decision is not related to a quality defect or safety issue. 

Member States affected

The discontinuations affect Member States differently. For more details, consult your country’s shortage register or contact your national competent authority. 

Monitoring of shortage

EMA’s Executive Steering Group on Shortages and Safety of Medicinal Products (MSSG) and EMA’s shortages working party (Medicines Shortages Single Point of Contact – SPOC - working party) are closely monitoring the supply situation and engaging with the marketing authorisation holder and other stakeholders to mitigate the impact of the planned discontinuations.

The SPOC Working Party Supports EMA’s MSSG and monitors and reports events that could affect the supply of medicines in the EU.

Recommendations for healthcare professionals

  • For information specific to your country, please consult your national shortage register or contact your national competent authority.
  • In affected Member States, healthcare professionals will receive a shortage communication letter with details on the impacted insulins and recommended actions.
  • Where applicable, healthcare professionals should transition patients currently using any of the affected insulins to suitable alternatives, in line with existing guidance and their clinical judgement.
  • Healthcare professionals should ensure that all patients are counselled on any changes in the new insulin regimen including the need to change dose and/or usage of the new insulin delivery system and additional glucose monitoring.
  • Close glucose monitoring is recommended when the patient is switched to another type or brand of insulin and in the initial weeks thereafter, especially in pregnant women and children who may need closer monitoring than the general population. The risk of hypoglycaemia may be higher in these populations.
  • Healthcare professionals may also contact relevant organisations for further information. A list of European not-for-profit organisations EMA engages with can be found on the EMA website.

Recommendations for patients and carers

  • For information specific to your country, please consult your national shortage register or contact your healthcare professional.
  • Your healthcare professional will advise you if any of the insulins you are using are affected by the discontinuation and will switch you to an alternative insulin, if needed.
  • If your healthcare professional switches your insulin they will explain any changes to you and ensure that you are given adequate training on using any new insulin delivery system.
  • If you are being switched, you may need to closely monitor your glucose levels during the transfer to another type or brand of insulin and in the initial weeks thereafter. This applies especially if you are pregnant or under 18 years of age, as you may be at higher risk of hypoglycaemia.
  • If you have any questions, speak to your doctor or pharmacist.
  • You may also contact relevant patients’ organisations for further information or support. A list of European not-for-profit organisations that EMA engages with can be found on the EMA website.
  • For additional information, consult your country’s shortage register or contact your national competent authority. 

Key facts

Medicines affected
Eli Lilly insulin (various forms)
Supply shortage status
Ongoing
Pharmaceutical forms affected
  • Solution for injection
  • Suspension for injection
Availability of alternatives
Yes

Key dates

First published

Related medicine information

Content above is reproduced from the official agency page (link below). We do not edit, interpret, or add to it.
🔬 Medical / technical details (for professionals)
Brand(s) / product name(s)
Agency-published detail

Forms: Solution for injection;Suspension for injection · Alternatives: Yes

First published
March 23, 2026
Last refreshed by us
1 month ago
Severity (as classified)
High
Official source
https://www.ema.europa.eu/en/medicines/human/shortages/eli-lilly-insulin-various-forms

All information on this page comes from the official agency notice. We translate and summarise it; we don't add or edit facts.

Related alerts

❓ Frequently asked questions

What is this medicine shortage alert about?
Eli Lilly insulin (various forms). Forms: Solution for injection;Suspension for injection · Alternatives: Yes
When was this alert issued?
This alert was issued on March 23, 2026 by EMA (European Medicines Agency).
Which countries are affected?
The alert applies to the entire EU.
How serious is this alert?
Serious risk. A serious risk means the product or medicine can cause significant harm. Treat the alert as urgent.
What should I do?
If you take this medicine, contact your pharmacist or prescribing doctor. They can advise on alternative products or substitutes. Do not stop taking prescription medicine without medical advice.
Where can I find the official notice?
The full official notice is published on www.ema.europa.eu.

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⚠️ We aggregate official notices. We do not give medical advice. For medical or legal decisions, consult the source agency and a qualified professional.